Autoimmunity & Inflammation
Reset
A complete root-cause framework for calming immune overactivation — healing the gut-immune axis, removing triggers, and rebuilding immune tolerance over eight structured weeks.
Gut Healing
5R Protocol
Elimination Diet
Lab Guided
“Autoimmunity is not the immune system attacking the self — it is a confused immune system that has lost the ability to distinguish self from non-self. That confusion has causes, and those causes can be found and removed.”
- 01
The Three Triggers of Autoimmunity
Alessio Fasano’s research identifies three factors required for autoimmunity to develop: genetic susceptibility, intestinal permeability (leaky gut), and an environmental trigger. You cannot change genetics — but you can heal the gut and remove the trigger. Two out of three removes the disease from expression.
- 02
The Gut-Immune Axis
70% of immune tissue (GALT — gut-associated lymphoid tissue) lines the intestinal wall. When the gut lining is compromised, undigested food particles and bacterial endotoxins cross into the bloodstream, activating immune responses that become chronic and eventually self-directed.
- 03
Molecular Mimicry — How Triggers Drive Autoimmunity
Certain proteins in foods (particularly gluten) share structural sequences with human tissue proteins. When the immune system creates antibodies against these food proteins, it can simultaneously attack the tissue they resemble — thyroid (Hashimoto’s), joints (rheumatoid arthritis), nervous system (MS).
- 04
Inflammation as the Perpetuating Force
Chronic inflammation keeps the immune system in a state of constant low-level activation. This is measured by inflammatory cytokines (IL-6, TNF-alpha) and acute phase proteins (hs-CRP). Until inflammation is reduced, the immune system cannot recalibrate — even with the best nutritional interventions.
- Remove gluten — completely, no exceptions
- Remove dairy — all forms for 8 weeks
- Remove refined sugar and processed foods
- Remove alcohol completely
- Vitamin D3 5,000 IU + K2 100mcg daily
- Omega-3 fish oil 2–3g EPA/DHA daily
- Curcumin + Piperine 500mg twice daily
- Switch to natural cleaning products
- Remove synthetic fragrances from home
- Switch personal care to natural alternatives
- Record symptom baseline scores 1–10
- Water filter if possible (heavy metals)
- Organic produce for the Dirty Dozen
- Remove non-stick cookware — use cast iron
- Check home for mould — especially bathroom
- Wild salmon 4x per week minimum
- Bone broth 1–2 cups daily
- Turmeric + black pepper in every meal
- Dark berries daily for polyphenols
- Add Mg Glycinate 300mg nightly
- Begin daily regulation practice (breathwork)
- Stress directly increases gut permeability
- Sleep 8 hrs minimum — immune repair occurs in sleep